Differentiation in Caenorhabditis Elegans

Write 6 pages with APA style on Differentiation in Caenorhabditis Elegans. When comparing it to that of human beings, it is small since humans have a large size genome (Yamamoto, 2011). Moreover, C. Elegans has a fast and suitable life cycle and can be manipulated in the laboratory. Therefore, C. Elegans was the first animal to have its genome completely sequenced. C. Elegans can be described as a simple organism that has a simple body system like an excretory system that will be explained later in this report. However, due to the simplicity, its cell lineage was completely mapped for all the 959 somatic cells in the adult worm. This report will also address brief anatomy, genetic, and the life cycle of this cell.One thing is known about c. Elegans is that it has six-chromosomes five of which pairs and form autosomal. The sixth chromosome is a sex chromosome. Hermaphrodites, however, have two X-chromosomes while the male has one X-chromosome thereby naming it as hemizygous. This means that they have only one chromosome instead of a pair. The one X-chromosome can, therefore, be produced if the hermaphrodite has lost one of the X-chromosome. It can also happen by mating with a male (Kulkarni, 2008).From the above genetic explanation, one of the reasons scientists worked with c. Elegans are because of their short life cycle as shown in Figure 1. Its life cycle depends on the surrounding temperatures. For instance, if the temperatures are 15 degrees Celsius, it takes five days to complete the lifecycle. If the temperatures are increased to 20 degrees Celsius, it will take three and a half days. Now, when the temperatures are 25 degrees Celsius, it will take 2.2 days to complete the same reproductive life cycle. The egg-fertilization of C. Elegans takes place in the adult hermaphrodite that it lays for a few hours. After about 40-cell stage, the eggs hatch and c. Elegance develop through four larval stages (Kulkalmi, 2011, p. 2). When it reaches the adult stage, it produces about 300 progeny and stays alive for around two weeks.On some occasions, especially when there is food deprivation or if c. Elegans is growing in a plate at the laboratory, it can take an alternative form of life known as the dauer larval stage as shown in Figure 1. Dauer larvae cannot eat since their mouths are plugged and also it has a thin body. Remarkably, dauers can stay alive for three months. However, they seem to be non-aging because they live for months until they consume food. It is after taking food that dauers enter the L4 stage where they live for more than the normal c. Elegans. It is because of this that c. Elegans leads to further research regarding anti-aging for human benefits.

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